PLEASE NOTE: I JUST LEARNED THAT FUROSEMIDE CAN ACTUALLY INCREASE BILIRUBIN LEVELS, SO IF YOUR LOVED ONE HAS AN EXTREMELY HIGH BILIRUBIN LEVEL THAT WON'T COME DOWN, PLEASE TALK WITH YOUR DOCTOR TO FIND OUT IF IT IS ABSOLUTELY NECESSARY THAT YOUR LOVED ONE HAS TO HAVE FUROSEMIDE, or if they can lower the dose. Furosemide also can cause kidney failure, shaking / "wobbliness," elevated glucose levels and more things you can read on THIS PAGE. I'm no doctor or rocket scientist, but I would think that if a person had a dangerously high bilirubin level that is extremely high, then I'd be a LOT more concerned with getting that Bilirubin level down, than taking Furosemide for diuretic purposes. PEOPLE TYPICALLY DIE IF THEIR BILIRUBIN GETS OVER 40 (and I'm pretty sure many people have died when it's in the 30s, as the body can be so fragile if things are that bad). Please check with your doctor, and use critical thinking with every bit of advice you get, no matter who it's from!

Blue light therapy for reducing Bilirubin Levels - Does it help?

I have a customer (whom I'll call Lisa) who is trying to save her son (whom I'll call Bruce), in the hospital. His Bilirubin level is 44, and his doctor said he has never seen anyone survive, when they have a level so high. I would really like to know why bilirubin lights are not used on adults who are in the ICU and have very high bilirubin levels! Am I missing something?? Why would this be used all over a baby's body, but not on adults??

I read that the bilirubin lights that are used on babies in the hospital, have a wavelength of 420 nm to 470 nm. Tonight I have been looking all over for a place where Lisa might be able to get these types of lights. I called Walgreens and the closest thing I can find, is a Neutrogena face mask, that does have some blue lights in it, and it does seem pretty bright, but it's mixed with red lights (which make it look pink). I do not know if that would affect the effectiveness of the light, so I kept looking (but I will put pics of the Neutrogena light, further down in this post). I did find a Walgreens that sells it, and that place is close to the hospital where her son is staying.

This is not the first time I've seen someone with a very high bilirubin level. I want to share this information here, in the event that it might help someone with cirrhosis. I don't know why it didn't occur to me to look up bilirubin light treatment before, but for whatever reason it just occurred to me today, so I'm posting that information here. You can get blue lights for as low as $34.95 on Amazon, and you might be able to get them at an Aquarium store.

Bili light

From Wikipedia, the free encyclopedia

Infant undergoing bili light therapy in a United States maternity ward.

A bili light^[1] is a light therapy tool to treat newborn jaundice (hyperbilirubinemia). High levels of bilirubin can cause brain damage (kernicterus), leading to cerebral palsy, auditory neuropathy, gaze abnormalities and dental enamel hypoplasia. The therapy uses a blue light (420-470 nm) that converts bilirubin into a form that can be excreted in the urine and feces. Soft eye shields are placed on the babies to protect their eyes from damage that may lead to retinopathy due to the bili lights.

PROTECTIVE EYEWEAR

If you buy these types of lights, you should use some kind of protective eyewear. I'm not an expert on this stuff, but I can see from the pictures that they cover the baby's whole eye area, so it might be best for you to do the same.

According to the reviews, these red googles appear to be the ones that would block the blue lights. I am NOT AN EXPERT ON THIS STUFF so I can't guarantee how well these work, and I encourage to do your own research, but if I were buying them for myself, to use with a blue light, these are probably the ones I'd get.

HDE Laser Eye Protection Safety Glasses for Green and Blue Lasers with Case (Red)

I don't know how the red ones work compared with these below, but I'd assume they are better. If you search the reviews for the red googles pictured above, you'll see a LOT of people talk about how they help block BLUE light, and I didn't do the search for the green ones below. This guy had a pretty detailed review so I think I would trust his opinion.

Austin Lyon

400nm-550nm

October 25, 2016

Color: Red Glasses w/ Black CaseVerified Purchase

Shipped and received quickly. Item as described. Looking for specific wavelegnth for safety purposes because the description is bland but I paid for it anyway. Waiting to test. Will shine a 1w laser through them and use a camera to see if even any IR gets through them. The 1w laser comes with its own protective eye wear so I will use those for when I test to be safe. I need to guarantee this product is effective before letting guests use it for protection. I would hate to rely on this bland description and cause a buddy to go blind. "Works with red and green lasers" doesnt quite cut it for me but they were cheap so I will do everyone a favor and check these out and post back within two weeks of halloween passing in 2016. Talk to ya soon

UPDATED: Received 15mw 532nm Nano laser from Wicked Lasers from an ebay seller. With protection on it looks like a dollar store laser dot, so I conclude there is protection. I am adding two images. One is of a gray dot(should be green but smartphones try to be smart). That is shining my laser through the glasses from point blank and the wall is 3 feet away from my laser so compare with the mext image of a green light taken a second later without the glasses filtering the beam. WORKS for 532nm guaranteed but will need to test my 450nm laser when it comes in.

Ok so my 450nm laser came in and so did a few 405nm lasers. I have found the ratings for these glasses. 400nm-550nm so do not expect these to protect against orange, red, or IR lasers.

BLUE LIGHTS

About the product

Stimulates collagen production which smoothes fine lines and wrinkles; Reduces pore size, scars, hyperpigmentation and age spot; Increase skin elasticity and improve circulation.
Wavelengths: Red Light (630nm), Blue Light (470nm), and Yellow Light (590nm).
Output Power: 25W - 420 LEDs total - 135 LEDs for red light, 135 LEDs for yellow light and 150 LEDs for blue light.
NORLANYA Photon Therapy Facial Salon Skin Care Treatment Machine

NORLANYA Photon Therapy Facial Salon Skin Care Treatment Machine

I hate to say I was surprised, but this product has an A rating on Fakespot.com! So I do believe this could be a legitimate product...

https://www.fakespot.com/product/norlanya-photon-therapy-facial-salon-skin-care-treatment-machine

ABI True 24W Blue LED PAR38 Grow Light for Aquarium and Plant Growth (450-460nm)

Simple Deluxe Clamp Lamp Light with 8.5 Inch Aluminum Reflector 150 Watt with 6 Feet Cord UL Listed

Simple Deluxe 2-Pack Clamp Lamp Light with 8.5 Inch Aluminum Reflector 150 Watt with 6 Feet Cord UL Listed

You will need to attach the lights to something. If you have something in your house that would work, that's great. You can probably come up with something that'd work. But If you want something that would be pretty easy to help you adjust the position, you could order one of these...

AmazonBasics Tripod Boom Microphone Stand

Pyle Universal Microphone Stand - M-6 Mic Holder USA Standard Adapter and Height Adjustable from 31.5” to 60” Inch High w/ Pivotable Gooseneck Mount - Heavy Duty Clutch Tension Knob PMKS32

If you want to be able to bend it further, you can add a 19-inch gooseneck attachment.

On Stage Microphone 19-inch Gooseneck, Black

I had pasted this first, until I remembered the clamp on lights, which are cheaper and probably just as effective, but I can't speak from experience. Just for yuks I am leaving this up... maybe if someone was into photography, they could use this for studio purposes, later : D.

StudioFX 400W Continuous Lighting Hairlight Boom Stand Set, Weight Bag Kit / Includes 85watt = 400 Watt CFL BULB / Weight Bag / Grip ARM

This man who is teaching about bilirubin, says in this video, that FUROSEMIDE can actually INCREASE BILIRUBIN LEVELS.

There are many drugs that can interfere with the hepatic uptake.

You can see Dr. Najeeb talk about this, in this video, below (which I've also featured on THIS PAGE), that Furosemide can increase bilirubin levels (note: Furosamide is a "sulfonamide" diuretic - you can see a study below). Please scroll to around the 46:30 mark in the video. He talks about how important "hepatic uptake" is. It displaces unconjugated bilirubin from plasma proteins.

The gist I get is that the unconjugated bilirubin is supposed to turn into the conjugated (water soluble) form so that it can be eliminated from the body, but furosemide can prevent this process from happening.

https://www.ncbi.nlm.nih.gov/pubmed/839387

The displacement of bilirubin from albumin by furosemide.

Shankaran S, Poland RL.

Abstract

Since furosemide, a sulfonamide diuretic, has been recommended for use in the newborn infant, a study was made of its effect on the bilirubin-binding capacity of albumin. Furosemide was compared to sulfisoxazole, a known displacer of bilirubin, by means of three methods. First, aliquots of whole blood from 20 icteric infants were diluted in phosphate buffer along with expected clinical concentrations of furosemide and sulfisoxazole. The red cells and globulins were then isolated and bilirubin concentrations were measured in these two fractions. The addition of Furosemide resulted in the displacement of bilirubin from albumin to red cells and globulins. Mole for mole, furosemide displaced bilirubin about as well as sulfisoxazole. Second, the hydroxybenzeneazobenzoic acid dye binding test of Porter and twaters was performed using the sera of eight jaundiced newborn infants. The mean dye binding capacity of the sera was significantly reduced with the addition of furosemide to a final concentration of 2 mug/ml. Third, the administration of furosemide (5 mg/kg) or sulfisoxazole (50 mg/kg) to adult Gunn rats resulted in a significant fall in mean serum bilirubin concentration compared to saline controls. Furosemide, like sulfisoxazole, is a potent displacer of bilirubin and should be used with caution in jaundiced infants.

PMID:: 839387

[Indexed for MEDLINE]

Effects of phototherapy on hepatic function in human alcoholic cirrhosis.

Knodell RG, Cheney H, Ostrow JD.

Abstract

Phototherapy has been used to treat neonatal jaundice, but little assessment has been made of possible beneficial effects on adult liver disease. Effects of phototherapy on bile acid turnover, biliary lipid concentration, liver function tests, and bromosulfophthalein (BSP) kinetics were studied in 8 alcoholic cirrhotics. Phototherapy initially increased biliary specific activity of both primary bile acids and then produced an acceleration of cholic and chenodeoxycholic acid decay curves. Pruritus was relieved in the 3 patients who had this symptom. The proposed mechanism for these changes is mobilization of bile acids from an expanded cutaneous bile acid pool with augmented bile acid excretion. No significant change in serum liver function tests or BSP plasma disappearance curves was seen. Phototherapy causes little improvement in intrinsic liver function, but produces specific changes in bile acid metabolism; these changes may be related to effects of light on a cutaneous bile acid pool.

Conventional Treatment for Jaundice

Neonatal

Light Therapy

Light therapy, or phototherapy, changes the shape and structure of bilirubin molecules so they can be excreted in the urine and stool. The baby is placed under special lighting that does not emit ultraviolet light. This is a relatively common form of therapy for jaundice, and proper nursing care enhances the effectiveness while minimizing complications. The baby wears a diaper and soft eye patches in order to protect her eyes from the light. Parents may notice that the baby may have frequent or loose bowel movements that are greenish in color; this is the body removing bilirubin through stool, and it should only be temporary. (14)

2006 Dec;6(6):303-12.

Fundamentals of phototherapy for neonatal jaundice.

Stokowski LA¹.

Author information

Erratum in

Adv Neonatal Care. 2007 Apr;7(2):65.

Abstract

Phototherapy is the use of visible light for the treatment of hyperbilirubinemia in the newborn. This relatively common therapy lowers the serum bilirubin level by transforming bilirubin into water-soluble isomers that can be eliminated without conjugation in the liver. The dose of phototherapy largely determines how quickly it works; the dose, in turn, is determined by the wavelength of the light, the intensity of the light (irradiance), the distance between the light and the infant, and the body surface area exposed to the light. Commercially available phototherapy systems include those that deliver light via fluorescent bulbs, halogen quartz lamps, light-emitting diodes, and fiberoptic mattresses. Proper nursing care enhances the effectiveness of phototherapy and minimizes complications. Caregiver responsibilities include ensuring effective irradiance delivery, maximizing skin exposure, providing eye protection and eye care, carefully monitoring thermoregulation, maintaining adequate hydration, promoting elimination, and supporting parent-infant interaction.

PMID:: 17208161
DOI:: 10.1016/j.adnc.2006.08.004

Blue(463 nm)---Excellent effect of kill bacteria, improve sensitive skin The blue light penetrating about 0.5mm has the function of calming against skin ; suitable for the skin which is sensitive, oily . It can adjust skin sebum secretion, effectively get rid of whelk to reach the aim of beautification. Besides, the blue light can astringe and tighten loosened skin.

Angel Kiss LED Photon Therapy Red Blue Green Light Treatment Facial Beauty Skin Care Phototherapy Mask for Home Use

https://www.fakespot.com/product/newkey-advanced-7-color-led-light-photon-therapy-system-facial-skin-care-beauty-mask

https://www.fakespot.com/product/norlanya-photon-therapy-facial-salon-skin-care-treatment-machine

About the product

Stimulates collagen production which smoothes fine lines and wrinkles; Reduces pore size, scars, hyperpigmentation and age spot; Increase skin elasticity and improve circulation.
Wavelengths: Red Light (630nm), Blue Light (470nm), and Yellow Light (590nm).
Output Power: 25W - 420 LEDs total - 135 LEDs for red light, 135 LEDs for yellow light and 150 LEDs for blue light.

The teacher mentioned something about the enzyme glucuronosyltransferase.... I don't have time to look it up now but am putting it here in case anyone else wants to reasearch it.

Glucuronosyltransferase - Wikipedia

https://en.wikipedia.org/wiki/Glucuronosyltransferase

A deficiency in the bilirubin specific form of glucuronosyltransferase is thought to be the cause of Gilbert's syndrome, which is characterized by unconjugated hyperbilirubinemia. It is also associated with Crigler-Najjar syndrome, a more serious disorder where the enzyme's activity is either completely absent (Crigler-Najjar ...

‎Function · ‎Diseases

https://www.google.com/search?q=bilirubin+glucuronyl+transferase+enzyme+deficiency&rlz=1C1CHBF_enUS696US696&oq=bilirubin+enzyme+transf&aqs=chrome.1.69i57j0.18655j1j7&sourceid=chrome&ie=UTF-8

https://books.google.com/books?id=IC28BAAAQBAJ&pg=PA247&lpg=PA247&dq=papaya+Glucuronosyltransferase&source=bl&ots=rldYOoF_PU&sig=CyeqhgmNImGOwIBHj6IqSNw7dEg&hl=en&sa=X&ved=0ahUKEwj2oYGSq77aAhVCylQKHT6tDEwQ6AEILzAD#v=onepage&q=papaya%20Glucuronosyltransferase&f=false